A day in the life of an Intersexed

Haha, ok I don't even know how to start this...

Preface: We do all the laundry in the house together to conserve energy, all the women in the house own the same shirt in size S and to top it off I own in the color gray One medium, three smalls, and one extra small.

I do not produce body odor. Simple fact.  I sweat, but no body odor.  I do not have to use deodorant. Freakish, I know.  I think this might be why my sense of smell is SO good.  

So yesterday I grabbed a clean, fresh out of the washer, gray v-neck t-shirt (Target: boyfriend tee) and threw it on.  It was a warm day and I sweat on the way to work no problem, I don't smell.  I get to work and within 7 minutes of me being there I start to smell Body Odor, B.O. No one is in the office. Instantly I know what's wrong.  I don't have my shirt on I have someone else's on.  (insert horribly disgusted face here)

(Now everyone produces body odor, unless you're a mutant, and wears deodorant and washes their clothes to combat the smell that stays in your clothes.  But little does anyone know that that smell rarely washes out.  And it stays in the clothes.  For this reason it is nearly impossible for me to wear another persons shirt, especially a fitted T.) 

What do I do!?  I instantly jump in the car and rush to target.  Grab 4 shirts off the shelf, walk straight back to the dressing rooms switch shirts, throw the B.O. one my purse and go to pay for the 4 new shirts I got.  

It doesn't stop there. 

I get back to the office in record time (20 minute turn around) and smell check myself only to find out that the Damn B.O. shirt got that persons B.O. on my skin.  So what do I do, take that shirt off, wash my armpits with soap and water and then wipe them down with 99% Isopropyl Alcohol and put my 3rd t-shirt on of the morning and thankfully the last of the day.

Sidenote: I understand that the general populous might think me freaking out over wearing someone else's shirt is a little overreaction, I understand. But ugh that smell is horrible.

The 1st BHRT Lab.

This is the first lab before I began my Bio-identical Hormone Replacement.  Labs were taken on 28 September 2009 at 11:45am.  Yes, I was fasting for 12 hours prior and was starving!  I believe my full panel is 12 vials of blood. 

What I really like about Dr. Filbeck is that he gives me a "Lab Summary" that is easier to read.  Here it is...

 

As you can see, on Page 2, I made notes during my appointment.  The 80 to the right of VitaminD, 25-Hydroxy is what I am aiming for.  

Also, on Page 3 under subjective, you can see the main reasons that brought me to try Bio-identical Hormone Replacement.  Extreme emotions, weeping, highly sensitive, numerous hot flashes.  

Extreme emotions:  I would move through emotions very quickly and erratically.  z.b. laughing to sobbing

Weeping:  I would break out into tears.  No reason, I was just so sad. 

Highly Sensitive:  I work at a pool and have for years, I fell into the pool (has happened before with no problems) and had a complete melt down.  Sobbing the works. 

OR

I would be writing a paper for my Language and Gender course at CSUSM and broke down into tears in the Library.  and on top of it I had to print the paper, drop it by my professors office hour (sprachstunde), and then go all the way to my car.  Completely embarrassed and emotionally wrecked.  

In all honesty, I was crazy.

LOW Vitamin D

Once my more current labs are scanned in you will be able to see my Vitamin D levels are extremely low, but for those of you who know you know that it is very difficult for my Vitamin D levels to go up.  This article might give an idea as to why.

Keep in mind this study was done with Rickets Mutants, or as the article gingerly puts it "Rickets-Associated Mutants"

Rational Design of Vitamin D3 Analogues Which Selectively Restore Activity to a Vitamin D Receptor Mutant Associated with Rickets

Steve L. Swann,, Joel J. Bergh,, M. Cindy Farach-Carson, and, John T. Koh

Organic Letters 2002 4 (22), 3863-3

Vitamin D₃-resistant rickets (VDRR) is associated with mutations to the Vitamin D receptor (VDR) which effect ligand-dependent transactivation...

these examples illustrate that small molecules may be used to restore activity to at least a subset of genetic mutations and suggest a potentially new pharmacological approach to the treatment of genetic disease...

A diverse class of human genetic diseases is associated with mutations to NHRs(nuclear hormone receptors), including androgen insensitivity syndrome (androgen receptor), resistance to thyroid hormone (RTH, thyroid hormone receptor), diabetes mellitus (peroxisome proliferator activated receptor), rickets (VDR), Cushings disease (glucocorticoid receptor), and certain forms of prostate and breast cancer (androgen and estrogen receptors).^7,8(

1. (7)Tenbaum, S.; Baniahmad, A. Int. J. Biochem. Cell Biol. 1997, 29, 1325−1341.

   [CrossRef], [PubMed], [CAS]
2. (8)Maslen, G. L.; Williams, T. D.; Lewis, H.; Schafer, A. J.; Chatterjee, V. K.; O'Rahilly, S.Nature 1999, 402, 880−882.

   [PubMed])

Basically, from what I am getting of the entire article Vitamin D_{3 can not be absorbed by certain mutants because or their mutation.}  

_{I wonder if that is why I cannot absorb} Vitamin D_3?

 

I am a MUTANT!

So I am doing research on CAIS, Testosterone Cypionate and all that lovely stuff.  I keep running across technical terminology such as,


 "N705S mutants" (C. Bohl et al J. Med. Chem., 2004, 47 (15), pp 3765–3776)  


Or, 


A diverse class of human genetic diseases is associated with mutations to NHRs, including androgen insensitivity syndrome (S. Swann et al. Org. Lett., 2002, 4 (22), pp 3863–3866)


and it just makes me laugh and think of X-men.  I can't help it. 


To all my other mutants out there...Hello!

Ordering My Meds

So I am ordering my new BHRT today.  I am currently on my standard 2mg estradiol, 200mg Progesterone, 2mg Testosterone.  Wondering if I should do less Testosterone.  I never know if the Testosterone does that much or not.

Anyways, I'm on the phone with Dr. Filbeck now asking what type of Testosterone I am on just for those of you who were wondering.

Testosterone Cypionate is the technical name of the testosterone.

Still waiting on the name of the Progesterone 

I just asked if I should get a blood test to see what the Testosterone is even doing to me on a technical level.  Will have an answer about the Progesterone and the Blood test on Monday.

Honesty Hour

Alright, Blatant Honesty Time!!!  So I can tell my hormones are a little off today.  I feel overwhelmed and a little ho hum.  Every time I go online and see a photo of someone with a newborn or even pregnant I just want to cry.  Now that is the hormones talking.

HF: Dienstag 14. Juni/ Mittwoch 15. Juni 2011

Hot Flash Counter:

Tuesday 14 June: 11:33-11:34am (1133-1134) 

Tingly skin on neck, arms, legs and chest.

Feels like your are sweating with fiberglass in your skin.

Wednesday 15 June: 11:31-11:32am (1131-1132)

Mild

Wednesday 15 June: 1:15pm (1315-1315)


Mild less than a minute